Monkey PD-1:PD-L1[Biotinylated] Inhibitor Screening Assay Kit
Cell signaling through the PD-1 receptor upon binding the PD-L1 ligand attenuates immune responses and this pathway is exploited by both tumors and viruses. The Monkey PD-1:PD-L1[Biotinylated] Inhibitor Screening Assay Kit is designed for screening and profiling inhibitors of this signaling pathway in the animal model cynomolgus monkey (Macaca fascicularis).
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PBS (Phosphate buffered saline)
Luminometer or microplate reader capable of reading chemiluminescence
Adjustable micropipettor and sterile tips
Catalog # | Component | Amount | Storage | |
71158 | PD-1 (Monkey), Fc fusion (Human IgG1) HiP™ | 10 µg | -80°C | Avoid freeze/ thaw cycles! |
71154 | PD-L1 (Monkey), Fc fusion (Human IgG1), Biotin-labeled HiP™ | 5 µg | -80°C | |
79311 | 3x Immuno Buffer 1 | 50 ml | -20°C | |
79728 | Blocking Buffer 2 | 50 ml | +4°C | |
79742 | Streptavidin-HRP | 10 µl | +4°C | |
79670 | ELISA ECL Substrate A | 6 ml | Room Temp | |
ELISA ECL Substrate B | 6 ml | Room Temp | ||
79699 | 96-well white microplate | 1 | +4°C |
1. Onlamoon, N. et al. Immunol. 2008, 124.1: 277-293 2. Wang. C. et al. Cancer Immunol. Res. 2014, 2.9: 846-856