Anti-PD-L1 (CD274) Neutralizing Antibody

Catalog #
71213
$285 *
Size: 100 µg
Qty
*US Pricing only. For international pricing, please contact your local distributor.
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Description

PD-L1 Neutralizing Antibody, recombinant humanized monoclonal, recognizing the extracellular domain of human PD-L1 and blocking the binding of PD-L1 to PD-1. This antibody has been shown to cross-react with mouse PD-L1. No other species have been tested.

This product has been cited 17 times.

Synonyms
PD-L1 Neutralizing Antibody, Programmed Cell Death 1 Ligand 1, PDL1, PD-L1, B7 homolog 1, B7H1, B7-H1, CD274, PDCD1L1
Product Info
Storage and Usage
Citations17
Species
Human
Isotype
IgG1κ
Clonality
Monoclonal
Host Species/Expression System
Freestyle 293 cells
Purification
Protein A affinity chromatography from HEK293 supernatants.
Format
Aqueous buffer solution.
Formulation
8 mM phosphate, 110 mM NaCl, 2.2 mM KCl, pH 7.4, and 20% glycerol
MW
50 and 25 kDa for the heavy and light chains, respectively (150 kDa).
Endotoxin Level
<1 EU/µg
Specific Activity
IC50 = 11.5 nM (human PD-L1) 1.8 nM (mouse PD-L1)
UniProt #
Q9NZQ7
Tag(s)
None
References

1. Freeman, G.J., et al., J. Exp. Med. 2000; 192(7): 1027-1034.
2. Dong, H., et al., Nat. Med. 1999; 5(12): 1365-1369.