In Vitro Toxicity Research Solutions

Early detection of toxicity

Before a drug can be tested in humans, it's essential to assess its safety profile. Now that U.S. Food and Drug Administration (FDA) no longer requires animal tests before human trials, assessing the potential toxicity of candidate drugs using in vitro systems is more critical than ever. In vitro testing allows researchers to identify potential toxic effects of drugs on various cell types or tissues without risking harm to humans or animals. When used early in the drug development process, it allows researchers to modify or discard compounds that demonstrate harmful effects before proceeding to more expensive and time-consuming animal testing or clinical trials. Furthermore, the ability to run automated high-throughput toxicity screens enables cost savings and efficiency. Additional testing using specific targets allows researchers to study the mechanisms underlying toxicity at the molecular level, guiding strategies on how to avoid or mitigate potential adverse effects.

Discovery tools for toxicity testing