Screening and Profiling Services

Evaluate lead compounds with our biochemical and cell-based screening services to identify specific inhibitors or activators. Save time by letting us screen your small molecules or biologics of interest against our unique assay panels or determine IC₅₀ values. With our portfolio of >600 assays available as a service, we’re here to help advance your drug discovery program.

Our biochemical-based inhibitor screening services provide excellent tools to quickly identify potential therapeutics, predict potency, and narrow down a large pool of candidates to a much smaller one.

To gain insight on cellular functional interventions, we also offer cell-based screening services. The cell-based data offers a more comprehensive view of the biological context and the resulting cellular responses, allowing for more informed decisions to be made about which compounds to advance to development.

Biochemical and Cell-Based Screening and Profiling Services

We are Uniquely Positioned for Your Discovery

Extensive Immunotherapy panels, including many unique immunotherapy targets
First commercially available and largest histone demethylase panel
Over 20 unique histone methyltransferases
Extensive SARS-CoV-2 assays, including 3CL Protease, RdRp, Papain-like Protease, and Spike:ACE2 binding assays

Complete PARP isozyme panel and unique PARP-trapping assays
Largest phosphodiesterase isozyme panel
First complete suite of HDAC and SIRT enzymes
Extensive bromodomain and HSP90 panels
Over 80 reporter cell lines for cell-based agonist or inhibitor screening and profiling, including many unique receptor/reporter combinations

Accelerating a Path to Discovery

We make the process simple to get you moving on the path of discovery quicker. It starts with your library, whether generated from AI modeling or based on an existing compound library. Select from our extensive portfolio of target-specific service assays, get a quote, and then ship your compounds. We can run single point or multi-point screens or obtain IC₅₀/EC₅₀ dose-response curves as defined in the quote and return results in 2 to 3 weeks depending on the service provided. Upon completion of service, you can choose to run additional screens, expand your compound profiling, or explore our off-the-shelf products to keep your research moving forward.