Heat Shock Protein Screening & Profiling

The HSP70 and HSP90 families of chaperone proteins help to process hundreds of proteins that are crucial in a myriad of cellular processes, including cell cycle control, cell signaling, cell survival, and apoptosis. In diseases such as cancer, they provide critical support for proteins responsible for tumorigenic pathways, such as signaling kinases, transcription factors, epigenetic regulators, and metabolic enzymes. Thus, HSP70 and HSP90 inhibitors show promise as therapeutics, but improved drugs with better toxicity, drug-resistance, and pharmacokinetic profiles are still required.

We offer HSP90α and HSP90β screening and profiling services that enable identification of N-terminal or C-terminal specific inhibitors, while our HSP70 screening service identifies inhibitors of ATP hydrolysis. Our team of experts, using our in-house developed biochemical assay kits, can provide:

  • Screening for activity across your compound library
  • Determination of IC50
  • Project guidance and questions answered in a timely manner
  • Delivery of detailed results promptly and on time
Heat Shock Protein Screening Services

If follow-up studies are required, we can provide the same active proteins as the ones used in our assays.

Learn more about the process and deliverables.

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*Alternative assay formats may be available. Inquire with our team to learn more. Export results View all selections

Note: Not all targets will have a commercially available reference control. Please inquire with our team if you need to furnish your own controls for specific targets.