Cell Lines

Cell lines have become an extremely useful tool for the study of protein interactions, gene activation, and other biological processes in a more natural biological system than cell-free assays. BPS has developed and selected for numerous stable cell lines that are applicable for a wide range of research applications. Additionally, BPS has a Cell Line Rental Program for select cell lines.

Luciferase Reporter Cell Lines
BPS’s cell signaling cell lines utilize the firefly luciferase reporter system. Our luciferase reporter constructs contain the firefly luciferase gene downstream of a response element that is specific for the particular cell signaling pathway being studied. Upon transcription factor binding to the response element, luciferase protein is transcribed. After addition of luciferin, luciferase converts luciferin to oxyluciferin in a reaction that gives off light. This bioluminescent reaction is readily detected and the amount of light given off is proportional to the amount of luciferase that has been transcribed and translated in the cells. Our portfolio is continually growing and currently includes a number of disease-relevant signaling pathways such as Notch, Wnt, Hippo, ARE, Gli, and many more.

BPS Bioscience provides signaling pathway screening services to investigate cell signaling pathways and signal transduction. In addition to luciferase reporter cell lines, BPS also offers cell lines for studying ion channels, ion transporters, phosphodiesterases, and G protein-coupled receptors (GPCRs). All of our cell lines have been extensively validated and are provided with detailed protocols that include instructions for general cell culture and maintenance, as well as example experimental setups. Each cell line is tested for viability and biological activity before shipping to ensure valid, reproducible results and to minimize the need for end-user optimization and troubleshooting.

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Catalog#SizeProduct NamePrice
60540 2 vials ADCC Bioassay Effector Cell F variant (Low Affinity) - Jurkat Recombinant Cell Line
$5,775
60541 2 vials ADCC Bioassay Effector Cell V variant (High Affinity) - Jurkat Recombinant Cell Line
$5,775
71273 2 vials ADCP Bioassay Effector Cell FcγRIIa (H variant) /NFAT Reporter-Jurkat
$5,775
79381 2 vials Adenosine A2A Receptor Functional Recombinant Cell Line
$9,250
60405 2 vials AP-1 Reporter – HEK293 Recombinant Cell Line (JNK signaling pathway)
$1,500
60612 500 reactions AP1 Reporter Kit (JNK Pathway)
$565
60513 2 vials ARE reporter cell line (Nrf2 antioxidant pathway)
$1,500
60514 500 reactions ARE Reporter Kit (Nrf2 Antioxidant Pathway )
$590
79617

100 ml
500 ml

Assay Medium 1B
Starting at:
$110
79621

100 ml
500 ml

Assay Medium 2A
Starting at:
$110
79619

100 ml
500 ml

Assay Medium 2B
Starting at:
$110
79623

100 ml
500 ml

Assay Medium 2C
Starting at:
$110
79476 2 Vials BTLA / NFAT - Luciferase Reporter - Jurkat Recombinant Cell Line
$8,800
79640 2 Vials CD123 (IL3Ra) - CHO Recombinant Cell Line (High, Medium, or Low Expression)
Starting at:
$6,000
60691 2 vials CD137 (4-1BB) HEK293 Recombinant Cell Line
$4,025
79289 2 vials CD137/NF-κB Reporter - HEK293 Recombinant Cell Line
$8,800
60523 2 vials CD137L (4-1BBL) CHO-K1 Recombinant Cell Line
$6,350
60537 2 vials CD155 (PVR) - HEK293 Recombinant Cell Line
$8,800
60548 2 vials CD155 / TCR Activator - CHO Recombinant Cell line
$8,800
79594 2 Vials CD160/NFAT - Luciferase Reporter - Jurkat Recombinant Cell Line
$8,800
79561-H 2 vials CD19 CHO Recombinant Cell Line (High Expression)
$6,000
79561-L 2 vials CD19 CHO Recombinant Cell Line (Low Expression)
$6,000
79561-M 2 vials CD19 CHO Recombinant Cell Line (Medium Expression)
$6,000
79624 2 Vials CD20 CHO Recombinant Cell Line (High or Medium Expression)
Starting at:
$6,000
79557-H 2 vials CD22 CHO Recombinant Cell Line (High Expression)
$6,000

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