Screening and Profiling Services

Evaluate lead compounds with our biochemical and cell-based screening services. Save time by letting us screen your compounds of interest against our unique assay panels or determine IC50 values with our portfolio of >200 assays so you can focus on advancing your drug discovery program.

Our biochemical-based screening services provide excellent tools to quickly identify potential therapeutics, predict potency, and narrow down a large pool of candidates to a much smaller one. However, these assays are not done in the context of live cells, and in the case of the immune checkpoint binding assays, they do not give any information on the functional result of the therapeutic intervention.

For this type of analysis, BPS offer cell-based screening services. The cell-based data offers a more comprehensive view of the biological context and the resulting cellular responses, allowing for more informed decisions to be made about which compounds advance and which need to be cut out.

With all screening and profiling services, we provide a comprehensive (>10 page) report with both raw and analyzed data, graphs, detailed protocols, etc. Since we produce our proteins and enzymes in-house for use with these assays, and we also supply the same proteins to many of the CRO’s and company’s offering HTS services, you can be confident that our quality and consistency are of the highest level. 

Screening Scientific Categories

Biochemical Assay Methods Available

  • AlphaScreen®
  • Chemiluminescent
  • Fluorescence Intensity
  • Fluorescence Polarization (FP)
  • Time-resolved fluorometric
  • TR-FRET/FRET

Custom Services and More