Metabolic Enzyme Screening & Profiling
Metabolic enzymes that regulate cellular energy pathways are essential for life. This includes all the processes required for material circulation and energy exchange, including catabolism and anabolism of nucleotides, sugars, proteins, and lipids. Metabolic pathway abnormalities have been correlated with diseases, such as diabetes and cancer, and are under investigation for targeted therapeutics.
We offer a selection of screening and profiling services to identify modulators of metabolic enzymes. Our team of experts, using our in-house developed biochemical assay kits, can provide:
- Screening for activity across your compound library
- Determination of IC50
- Project guidance and questions answered in a timely manner
- Delivery of detailed results promptly and on time
If follow-up studies are required, we can provide the same active proteins as the ones used in our assays.
Inputs and outputs of select mammalian cell metabolic pathways and the connections between pathways are illustrated above.
Learn more about the process and deliverables.
Available Service Assays
Note: Not all targets will have a commercially available reference control. Please inquire with our team if you need to furnish your own controls for specific targets.
- Heat Shock Protein Screening Services
- PCSK9 Screening & Profiling Services
- Custom Biochemical Assay Development