Methyl-lysine Reader Screening & Profiling

Methyl-lysine reader proteins specifically recognize methylated lysine on histone tails and help to convey this epigenetic modification by recruiting activating or repressive factors regulating downstream processes such as cell cycle regulation, stress responses, development processes, or oncogenesis. Their involvement in cancer makes them attractive therapeutic targets.

We offer a selection of screening and profiling services to identify inhibitors of methyl-lysine reader binding to target substrates. Our team of experts, using our in-house developed biochemical assay kits, can provide:

• Screening for activity across your compound library
• Determination of IC₅₀
• Project guidance and questions answered in a timely manner
• Delivery of detailed results promptly and on time