Methyl-lysine Reader Screening & Profiling

Methyl-lysine reader proteins specifically recognize methylated lysine on histone tails and help to convey this epigenetic modification by recruiting activating or repressive factors regulating downstream processes such as cell cycle regulation, stress responses, development processes, or oncogenesis. Their involvement in cancer makes them attractive therapeutic targets.

We offer a selection of screening and profiling services to identify inhibitors of methyl-lysine reader binding to target substrates. Our team of experts, using our in-house developed biochemical assay kits, can provide:

  • Screening for activity across your compound library
  • Determination of IC50
  • Project guidance and questions answered in a timely manner
  • Delivery of detailed results promptly and on time
Methyl-Lysine Reader Screening and Profiling Services

If follow-up studies are required, we can provide the same active proteins as the ones used in our assays.

Learn more about the process and deliverables.

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*Alternative assay formats may be available. Inquire with our team to learn more. Export results View all selections

Note: Not all targets will have a commercially available reference control. Please inquire with our team if you need to furnish your own controls for specific targets.