PD-L1 (CD274), Fc fusion (Mouse) HiP™ Recombinant

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Catalog #
71117
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Description

Mouse secreted Programmed Cell Death 1 Ligand 1 (PD-L1)-Fc fusion protein, also known as CD274 and B7 homolog 1 (B7- H1), GenBank Accession No. NM_021893, a.a. 19-238, fused at the C-terminus to the Fc portion of mouse IgG2a, expressed in a HEK293 cell expression system. MW = 51.8 kDa.

Synonyms
Programmed Cell Death 1 Ligand 1, CD274, B7 homolog 1 (B7-H1)
Product Info
Storage and Usage
Citations
Species
Mouse
Host Species/Expression System
HEK293
Purity

≥90%

Format
Aqueous buffer solution
Formulation
8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
MW
51.8 kDa
Amino Acids
19-238
Genbank #
NM_021893
UniProt #
Q9EP73
Tag(s)
C-terminal Fc fusion (Mouse IgG2a)
References

1. Freeman, G.J., et al., J. Exp. Med. 2000; 192(7):1027-34.
2. Dong, H., et al., Nat. Med. 1999; 5(12):1365-9.

Product Specific Reference(s): 
1. Lmai, Y., et al., J. Immunol. 2015; 195(2): 421-425. 

Application Reference(s):

1. Functional and mechanistic advantage of the use of a bifunctional anti-PD-L1/IL-15 superagonist (2020)