PD-1 CHO Cell Line
PD-1 CHO Cell Line is a clonal stable CHO-K1 cell line constitutively expressing human PD-1 receptor (accession number: NM_005018). This cell line has been validated for surface expression of human PD-1 by flow cytometry.
Purchase of this cell line is for research purposes only; commercial use requires a separate license. View the full terms and conditions.
Name | Ordering Information |
Thaw Medium 3 | BPS Bioscience #60186 |
Growth Medium 3B | BPS Bioscience #79529 |
The cell line has been screened to confirm the absence of Mycoplasma species.
PD-1 (Programmed Death Protein 1, CD279) is a transmembrane protein expressed on the surface of immune cells that binds to PD-L1 or PD-L2, inducing apoptosis of T cells and inhibiting immune responses. Cancer cells often overexpress PD-L1 or PD-L2, allowing them to suppress T cell activation, evade the host immune response, and proliferate. Thus, disrupting the PD-1 co-inhibitory pathways may be an effective approach to developing anti-cancer therapies, as well as other immune diseases like multiple sclerosis, arthritis, lupus, and type I diabetes. The overexpression of PD-1 in this cell line allows for the study of PD-1 antibodies and other novel therapeutics.