PKCν (PKCnu), GST-tag Recombinant

Catalog #
40167
$345 *
Size: 10 µg
Qty
*US Pricing only. For international pricing, please contact your local distributor.
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Description

Recombinant human PKCν (PKCnu), full length, with N-terminal GST-tag, expressed in Sf9 insect cells via a baculovirus expression system.

Synonyms
EPK2; PRKCN; PKD3; nPKC-NU; PKCν protein kinase c nu
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
Sf9 insect cells
Purity
≥75%
Format
Aqueous buffer solution
Formulation
50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.
MW
142 kDa
Amino Acids
full length
Genbank #
NM_005813
UniProt #
O94806
Tag(s)
N-terminal GST-tag
Background
PKCν , also known as PKD3, is a members of the protein kinase C (PKC) family of serine/threonine kinases that play critical roles in the regulation of cellular differentiation and proliferation in many cell types. PKCν is composed of 890 amino acid residues and the protein has 77.3% similarity to human PKCµ (PKCmu) and 77. 4% similarity to mouse PKD (1). The PKCν mRNA is ubiquitously expressed in various tissues and the gene is located between markers WI-9798 and D2S177 on chromosome 2p21 region.
References
Hayashi,A. et al: PKCnu, a new member of the protein kinase C family, composes a fourth subfamily with PKCmu. Biochim Biophys Acta. 1999 May 6;1450(1):99-106.