Virus-Based Tools
Virus-based tools such as Lentivirus, Adeno-Associated Virus (AAV), and Vesicular Stomatitis Virus (VSV) are critical for cell engineering and the study of viral infection. We have designed a suite of ready-to-use viral reagents to address a wide span of research areas including virology (particularly Coronaviruses), immunotherapy, CAR-T therapy, CRISPR, cell signaling, and more.
Custom development is available across all viral product types. Contact us for more information.
Comparison of Virus-Based Products
| HIV-based lentivirus | VSV Delta G | AAV | |
| Genome size | 9.7 kb | 11 kb | 4.7 kb |
| Suggested max insert size | 10 kb | 4.5 kb | 2.5 kb |
| Genome type | ssRNA | ssRNA | ssDNA |
| Pseudotyping | Yes | Yes | No |
| Integration | Yes - stable (retrovirus) | No | No |
| Transduce exogenous gene of interest | Yes - stable | Yes - transient | Yes > 6 months |
| Time to peak expression | 72 hours | 24-48 hours | 7 days (2 weeks in vivo) |
| Biosafety level | 2 | 2 | 1 |
| In vivo use (animals) | Low efficiency | - | Most suitable |
| Immune response | Yes, medium | - | Ultra-low |
| Prefered applications | Gene transfer (in vitro, stable) | Model viral infection | Gene transfer (in vitro and in vivo) |
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│Featured Products
- CRISPR/Cas9 Kinase Knockout Lentivirus Library
- Reporter AAV Products
- Spike (BA.4/5, Omicron Variant) (SARS-CoV-2) Pseudotyped Lentivirus (Luc Reporter)
- Spike (BA.4/5, Omicron Variant) (SARS-CoV-2) Pseudotyped VSV Delta G (Luciferase Reporter)
- Cas9 Lentivirus (Neomycin Selection)
- eGFP Lentivirus (Inducible TET On)
- NF-κB Luciferase Reporter Lentivirus
- Spike (SARS-CoV-2) Pseudotyped Lentivirus (Luciferase Reporter)
