PKCµ (PKCmu), GST-tag Recombinant

Catalog #

40166

$345 *

Size: 10 µg

Qty

Bulk/Custom

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Synonyms

PKD; PKCM; PRKCM, PKCµ protein kinase c mu

Product Info

Storage and Usage

Citations

Species

Human

Host Species/Expression System

Sf9 insect cells

Purity

≥75%

Format

Aqueous buffer solution

Formulation

50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.

131 kDa

Amino Acids

full length

Genbank #

X75756

UniProt #

Q15139

Tag(s)

N-terminal GST-tag

Background

Protein kinase Cmu (PKCµ) is a member of the protein kinase C (PKC) family that differs from the other PKC isoenzymes in structural and enzymatic properties. PKCµ is a ubiquitous in nature with the highest expression in the thymus, lung and peripheral blood mononuclear cells (1). PKCµ forms a complex in vivo with a phosphatidylinositol 4-kinase and a phosphatidylinositol-4-phosphate 5-kinase. A region of PKCµ between the amino-terminal transmembrane domain and the pleckstrin homology domain is shown to be involved in the association with the lipid kinases (2).

References

1. Rennecke, J. et al: Immunological demonstration of protein kinase C mu in murine tissues and various cell lines. Eur J Biochem. 1996 Dec 1;242(2):428-32.
2. Nishikawa, K. et al: Association of protein kinase Cmu with type II phosphatidylinositol 4-kinase and type phosphatidylinositol-4-phosphate 5-kinase. J Biol Chem. 1998 Sep 4;273(36):23126-33.

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PKCµ (PKCmu), GST-tag Recombinant

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