EPOR-(GSSG)6- JAK2(V617F, Y1007F, Y1008F) Recombinant
Catalog #
100713
$355
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Description
Complex of Human EPOR, also known as Erythropoietin receptor, GenBank Accession No. NM_000121, a.a. 273-338 with N-terminal His-tag, MW=9 kDa, and JAK2, also known as Janus Kinase 2, with V617F, Y1007F and Y1008F mutations, GenBank Accession No. NM_004972, a.a. 36-1132(end), with N-terminal FLAG-tag, MW=128 kDa. The proteins were expressed as single fusion protein with a (GSSG)6 linker in a Baculovirus infected Sf9 cell expression system.
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Synonyms
Janus Kinase 2 complex, Erythropoietin receptor complex
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Product Data Gallery
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
Sf9 insect cells
Purity
89%
Supplied As
Aqueous buffer solution.
Formulation
50 mM Tris-HCl pH 8.0, 500 mM NaCl, 10% glycerol, 3 mM DTT.
MW
EPOR: 9 kDa, JAK2: 128 kDa
Amino Acids
EPOR: 273-338, JAK2: 36-1132(end)
Genbank #
EPOR: NM_000121, JAK2: NM_004972
UniProt #
EPOR: P19235, JAK2: O60674
References
1. Tono, C., et al., Leukemia. 2005; 19(10): 1843-1844.
2. Goerttler, P.S., et al., Blood. 2005; 106(8): 2862-2864.