JAK2 (V617F, Y1007F, Y1008F)- (GSSG)8-EPOR Recombinant

Catalog #

100709

$355 *

Size: 10 µg

Qty

Bulk/Custom

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Description

Complex of Human JAK2, also known as Janus Kinase 2, with V617F, Y1007F and Y1008F mutations, GenBank Accession No. NM_004972, a.a. 36-1132(end), with N-terminal FLAG-tag, MW=128 kDa, and human EPOR, also known as Erythropoietin receptor, GenBank Accession No. NM_000121, a.a. 273-338 with N-terminal His-tag, MW=9 kDa. The proteins were expressed as single fusion protein with a (GSSG)₈ linker in a Baculovirus infected Sf9 cell expression system.

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Synonyms

Janus Kinase 2 complex, Erythropoietin receptor complex

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Product Data Gallery

4-20% SDS-PAGE Coomassie Staining

Product Info

Storage and Usage

Citations

Species

Human

Host Species/Expression System

Sf9 insect cells

Purity

87%

Supplied As

Aqueous buffer solution.

Formulation

50 mM Tris-HCl pH 8.0, 500 mM NaCl, 10% glycerol, 3 mM DTT.

JAK2: 128 kDa, EPOR: 9 kDa

Amino Acids

JAK2: 26-1132(end), EPOR: 273-338

Genbank #

JAK2: NM_004972, EPOR: NM_000121

UniProt #

JAK2: O60674, EPOR: P19235

Tag(s)

JAK2: N-terminal FLAG-tag, EPOR: N-terminal His-tag

References

1. Tono, C., et al., Leukemia. 2005; 19(10): 1843-1844.
2. Goerttler, P.S., et al., Blood. 2005; 106(8): 2862-2864.

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JAK2 (V617F, Y1007F, Y1008F)- (GSSG)8-EPOR Recombinant

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