JAK2 (JH2 Domain) (E596A, V617F, W659A, W777A, F794H), His-Tag Recombinant

Catalog #

100122

$390 *

Size: 20 µg

Qty

Bulk/Custom

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Description

Recombinant human JAK2 (Janus Kinase 2) encompassing amino acids 536-812, containing the pseudo-kinase domain JH2 with mutations E596A, V617F, W659A, W777A, and F794H. This construct contains a C-terminal His-tag (6xHis). The protein was affinity purified.

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Synonyms

Janus kinase-2, Just Another Kinase 2, JTK10, JAK2, JAK-2, JH2, JH-2

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Product Data Gallery

4-20% SDS-PAGE Coomassie Staining

Product Info

Storage and Usage

Citations

Species

Human

Construct

JAK2 (E596A, V617F, W659A, W777A, F794H) (535-812-His)

Mutation

E596A, V617F, W659A, W777A, F794H

Host Species/Expression System

Sf9

Purity

≥90%

Format

Aqueous buffer solution.

Formulation

20 mM Tris-HCI pH 8.5, 0.5 mM TCEP and 10% glycerol.

33 kDa

Amino Acids

535-812

Genbank #

NM_004972

UniProt #

O60674

Tag(s)

C-terminal His-tag

References

1. Tono, C., et al., Leukemia. 2005; 19(10): 1843-1844.

2. Goerttler, P.S., et al., Blood. 2005; 106(8): 2862-2864.

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JAK2 (JH2 Domain) (E596A, V617F, W659A, W777A, F794H), His-Tag Recombinant

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