JAK2 (W659A, W777A, F794H) (JH2 Domain), His-Avi-Tag, Biotin-Labeled Recombinant

Catalog #

79463

$405 *

Size: 10 μg

Qty

Bulk/Custom

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Description

Recombinant human JAK2 (Janus Kinase 2) encompassing amino acids 536-812, containing the pseudo-kinase domain JH2 with mutations W659A, W777A and F794H. This construct contains a C-terminal His-tag (6xHis) followed by an Avi-Tag™. The protein was enzymatically biotinylated using the Avi-Tag™ and affinity purified.

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Synonyms

Jak2, W659A, W777A, F794H, jak, JTK10, Just Another Kinase, tyrosine protein kinase JAK2, JAK-2

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Product Data Gallery

4-20% SDS-PAGE Coomassie Staining

Biotin-Avidin Pulldown

Product Info

Storage and Usage

Citations

Species

Human

Construct

JAK2 (W659A, W777A, F794H) (536-812-His-Avi)-(Biotin)

Mutation

W659A, W777A, F794H

Host Species/Expression System

Sf9

Purity

≥90%

Format

Aqueous buffer solution.

Formulation

40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, 0.04% Tween20, 140 mM Imidazole and 20% glycerol.

35 kDa

Amino Acids

536-812

Genbank #

NM_004972

UniProt #

O60674

Tag(s)

C-Terminal His-Avi-Tag

Label

This protein is enzymatically biotinylated using Avi-Tag™ technology. Biotinylation is confirmed to be ≥90%.

For more information on enzymatic biotinylation, please see our Tech Note.

References

1. Tono, C., et al., Leukemia. 2005; 19(10): 1843-1844.

2. Goerttler, P.S., et al., Blood. 2005; 106(8): 2862-2864.

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JAK2 (W659A, W777A, F794H) (JH2 Domain), His-Avi-Tag, Biotin-Labeled Recombinant

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