CD8B, Avi-His-Tag Recombinant

Only %1 left

Catalog #

101843

As low as $265 *

Cat # Size Price*

Qty

Bulk/Custom

Add to Favorites

*US Pricing only. For international pricing, please contact your local distributor.

●

Purchase

●

Description

Recombinant human CD8b (cluster of differentiation 8 b), encompassing amino acids 22-170. This construct contains a C-terminal Avi-Tag™ followed by a His-Tag (6xHis). This protein was affinity purified.

●

Synonyms

T-cell surface glycoprotein CD8 beta chain, CD8b, CD8B1

●

Product Data Gallery

4-20% SDS-PAGE Coomassie Staining

Product Info

Storage and Usage

Citations

Species

Human

Construct

CD8B (22-170-Avi-His)

Host Species/Expression System

HEK293

Purity

≥90%

Format

Aqueous buffer solution.

Formulation

8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol

20 kDa + glycans

Amino Acids

22-170

Glycosylation

This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Genbank #

NM_172213.5

UniProt #

P10966

Tag(s)

C-terminal Avi-Tag™, His-Tag

Background

CD8 is a co-receptor for the TCR (T cell receptor) in T cells, binding to MHC (major histocompatibility complex) class I proteins. CD8 is a typical marker of cytotoxic T cells and is involved in signaling. CD8 has two isoforms, a and b. CD8b recruits Lck (lymphocyte-specific protein tyrosine kinase) to the TCR-CD3 complex, and Lck phosphorylates multiple proteins involved in activation of CTLs (cytotoxic T-lymphocytes). It is thus critical for the lysis of cancer cells.

Skip to the end of the images gallery

Skip to the beginning of the images gallery

●

Datasheets/Protocols

101843 Lot 230602

Datasheets provide example lot-specific information. Contact us to request information on currently available lots.

● General Protocols

● FAQs

● Contact Technical Service

CD8B, Avi-His-Tag Recombinant

PRODUCTS

SERVICES

RESOURCES

COMPANY