ACE2 Lentivirus

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Catalog #
79944
$835 *
Size: 500 µl x 2
Qty
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Description

Human Angiotensin converting enzyme 2 (ACE2), also known as ACEH, is an integral membrane protein found on the surface of cells in the lungs, arteries, heart, kidney, and intestines. ACE2 serves as the entry point into cells for some coronaviruses, including the two strains that caused outbreaks of Severe acute respiratory syndrome (SARS-CoV) and coronavirus disease 2019 (COVID-19) (SARS-CoV-2).


The ACE2 Lentivirus are replication incompetent, HIV-based, VSV-G pseudotyped lentiviral particles that are ready to be transduced into almost all types of mammalian cells, including primary and non-dividing cells. The particles contain an ACE2 gene (NM_021804.3) driven by an EF1A promoter (Figure 1).

 

ACE2 Lentivirus

Figure 1. Schematic of the lenti-vector used to generate the ACE2 lentivirus

This product has been cited 7 times.

Synonyms
Angiotensin converting enzyme 2, ACEH, ACE2 cells, ACE2 cell assay
Product Info
Storage and Usage
Citations7
Supplied As
Two vials (500 μl x 2) of lentivirus at a titer ≥5 x 106 TU/ml. The titer will vary with each lot; the exact value is provided with each shipment.
Formulation

The lentiviruses were produced from HEK293T cells in medium containing 90% DMEM + 10% FBS.

Genbank #
NM_021804.3