Spike Trimer (S1+S2) (K417T, E484K, N501Y), His-Tag (SARS-CoV-2) Recombinant
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Catalog #
100988
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$320
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Description
Recombinant SARS-CoV-2 Spike protein in its homotrimeric form, containing S1+S2 subunits and encompassing amino acids 16-1213. This protein contains three mutations K417T, E484K and N501Y that have been found in SARS-CoV-2 variants of concern and may lead to higher transmissibility. The construct also contains mutations 682RRAR685>A, K986P and V987P, and a T4 trimerization domain followed by a His-tag (6xHis) in C-terminal. The recombinant protein was affinity purified.
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Synonyms
sars cov 2 Spike, K417T mutation, Brazil coronavirus, South Africa variant
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Product Data Gallery
Product Info
Storage and Usage
Citations
Species
SARS-CoV-2
Construct
Spike Trimer (K417T, E484K, N501Y)(16-1213-His) (SARS-CoV-2)
Mutation
K417T, E484K, N501Y
Host Species/Expression System
HEK293
Purity
>90%
Supplied As
Aqueous buffer solution.
Formulation
8 mM phosphate pH 7.4, 110 mM NaCl, 2.2 mM KCl, 20% glycerol
MW
137 kDa +glycans
Amino Acids
16-1213
Glycosylation
This protein runs at higher M.W. by SDS-PAGE due to glycosylation.
Genbank #
MN908947
UniProt #
P0DTC2