Spike Trimer (S1+S2) (B.1.1.7, Alpha Variant), His-Tag (SARS-CoV-2) Recombinant

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Catalog #

510334

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Description

Recombinant SARS-CoV-2 Spike protein in its homotrimeric form, containing S1+S2 subunits and encompassing amino acids 16-1213. This protein corresponds to SARS-CoV-2 Variant B.1.1.7, also known as variant Alpha originally discovered in the United Kingdom. It contains mutations N501Y, A570D, D614G, P681H, T716I, S982A, D1118; deletions: 21765:6 (69-70HV), 21991:3 (144Y). The construct also contains mutations 682RRAR685>A, K986P and V987P, and a T4 trimerization domain followed by a His-tag (6xHis) in C-terminal. The recombinant protein was affinity purified.

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Synonyms

sars cov 2 Spike Trimer, Lineage B.1.1.7

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Product Data Gallery

4-20% SDS-Page Coomassie Staining

Product Info

Storage and Usage

Citations

Species

SARS-CoV-2

Construct

Spike Trimer (B.1.1.7) (SARS-CoV-2) (16-1213-His)

Mutation

Deletions: del69–70 HV, del144 Y

Substitutions: N501Y, A570D, D614G, P681H, T716I, S982A, D1118H

Host Species/Expression System

HEK293

Purity

≥90%

Supplied As

Aqueous buffer solution.

Formulation

8 mM phosphate pH 7.4, 110 mM NaCl, 2.2 mM KCl, 20% glycerol.

137 kDa

Amino Acids

16-1213

Glycosylation

This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Genbank #

MN908947

UniProt #

P0DTC2

Tag(s)

C-terminal His-tag

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Spike Trimer (S1+S2) (B.1.1.7, Alpha Variant), His-Tag (SARS-CoV-2) Recombinant

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