Spike Trimer (S1+S2) (P.1 Variant), His-Tag (SARS-CoV-2) Recombinant

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Catalog #

100989

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Description

Recombinant SARS-CoV-2 Spike protein in its homotrimeric form, containing S1+S2 subunits and encompassing amino acids 16-1213. This protein corresponds to SARS-CoV2 Variant P.1, also known as variant Gamma, originally discovered in Brazil. It contains 11 mutations, as listed below. The construct also contains mutations 682RRAR685>A, K986P and V987P, and a T4 trimerization domain followed by a His-tag (6xHis) in C-terminal. The recombinant protein was affinity purified.

This product has been cited 2 times.

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Synonyms

Brazilian variant, gamma, P.1

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Product Data Gallery

4-20% SDS-Page Coomassie Staining

Product Info

Storage and Usage

Citations2

Species

SARS-CoV-2

Construct

Spike Trimer (P.1) (16-1213-His) (SARS-CoV-2)

Mutation

L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y, T1027I

Host Species/Expression System

HEK293

Purity

≥90%

Supplied As

Aqueous buffer solution.

Formulation

8 mM phosphate pH 7.4, 110 mM NaCl, 2.2 mM KCl, 20% glycerol

137 kDa + glycans

Glycosylation

This protein runs at higher M.W. by SDS-PAGE due to glycosylation.

Genbank #

MN908947

UniProt #

P0DTC2

Tag(s)

C-terminal His-tag

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Spike Trimer (S1+S2) (P.1 Variant), His-Tag (SARS-CoV-2) Recombinant

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