UNC0321 (TFA salt)
Catalog #
27306
$640
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Description
UNC0321 (trifluoroacetate salt) is a selective histone lysine methyltransferase (HMTase) inhibitor for G9a and GLP (also known as EHMT1), with IC50 of 6 nM and 15 nM, respectively. It is more than 40,000-fold more selective for G9a and GLP vs. SET7/9, SET8, PRMT3, or JMJD2E.
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Synonyms
4-Quinazolinamine, 7-[2-[2-(dimethylamino)ethoxy]ethoxy]-2-(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)-6-methoxy-N-(1-methyl-4-piperidinyl)-, trifluoroacetate
Product Info
Storage and Usage
Citations
Purity
≥95%
Format
White crystalline powder
Formula
C27H45N7O3 • 3(CF3COOH)
MW
857.8 Da
Solubility
Soluble in DMSO.
CAS Registry #
1238673-32-9 (free base)
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