Spike Neutralizing Antibody (Clone G10xA5) (SARS-CoV-2)

Catalog #
101327
$600 *
Size: 100 µg
Qty
*US Pricing only. For international pricing, please contact your local distributor.
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Description

This monoclonal antibody recognizes the SARS-CoV-2 Spike (B.1.1.529, Omicron Variant) RBD Domain and the S1+S2 trimeric complex to neutralize its interaction with ACE2 [Table of variants]. The human ACE2 receptor is found on the surface of type I and II pneumocytes, endothelial cells, and ciliated bronchial epithelial cells. ACE2 is known to mediate COVID-19 infection through direct binding of the SARS-CoV-2 Spike protein. This neutralizing antibody has been functionally tested using the SARS-CoV-2 Spike RBD (B.1.1.529, Omicron Variant):ACE2 Inhibitor Screening Colorimetric Assay Kit (BPS Bioscience #78339).

Synonyms
coronavirus antibody, omicron antibody, Omicron RBD Antibody
Product Info
Storage and Usage
Citations
Isotype
Human IgG1κ
Purification
Protein A affinity chromatography
Format

Aqueous buffer solution

Formulation

1X PBS, 0.2% BSA

Specificity

The antibody recognizes the B.1.1.529 Omicron variant RBD domain and the S1+S2 trimeric protein.  It has not been tested on other spike variants, or on the S1 subunit.

MW
~150 kDa