Spike Neutralizing Antibody (Clone G10xA1) (SARS-CoV-2)
This monoclonal antibody recognizes the SARS-CoV-2 Spike (B.1.1.529, Omicron Variant) RBD Domain and the S1+S2 trimeric complex to neutralize its interaction with ACE2 [Table of variants]. The human ACE2 receptor is found on the surface of type I and II pneumocytes, endothelial cells, and ciliated bronchial epithelial cells. ACE2 is known to mediate COVID-19 infection through direct binding of the SARS-CoV-2 Spike protein. This neutralizing antibody has been functionally tested using the SARS-CoV-2 Spike RBD (B.1.1.529, Omicron Variant):ACE2 Inhibitor Screening Colorimetric Assay Kit (BPS Bioscience #78339).
Aqueous buffer solution
1X PBS, 0.2% BSA
The antibody recognizes the B.1.1.529 Omicron variant RBD domain and the S1+S2 trimeric protein. It has not been tested on other spike variants, or on the S1 subunit.
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