Cell Lines

 

Cell lines have become an extremely useful tool for the study of protein interactions, gene activation, and other biological processes in a more natural biological system than cell-free assays. BPS has developed and selected for numerous stable cell lines that are applicable for a wide range of research applications. Additionally, BPS has a Cell Line Rental Program for select cell lines.

Luciferase Reporter Cell Lines
BPS’s cell signaling cell lines utilize the firefly luciferase reporter system. Our luciferase reporter constructs contain the firefly luciferase gene downstream of a response element that is specific for the particular cell signaling pathway being studied. Upon transcription factor binding to the response element, luciferase protein is transcribed. After addition of luciferin, luciferase converts luciferin to oxyluciferin in a reaction that gives off light. This bioluminescent reaction is readily detected and the amount of light given off is proportional to the amount of luciferase that has been transcribed and translated in the cells. Our portfolio is continually growing and currently includes a number of disease-relevant signaling pathways such as Notch, Wnt, Hippo, ARE, Gli, and many more.

BPS Bioscience provides signaling pathway screening services to investigate cell signaling pathways and signal transduction. In addition to luciferase reporter cell lines, BPS also offers cell lines for studying ion channels, ion transporters, phosphodiesterases, and G protein-coupled receptors (GPCRs). All of our cell lines have been extensively validated and are provided with detailed protocols that include instructions for general cell culture and maintenance, as well as example experimental setups. Each cell line is tested for viability and biological activity before shipping to ensure valid, reproducible results and to minimize the need for end-user optimization and troubleshooting.

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Catalog#SizeProduct NamePrice
60540 2 vials ADCC Bioassay Effector Cell F variant (Low Affinity) - Jurkat Recombinant Cell Line Contact us for pricing
60541 2 vials ADCC Bioassay Effector Cell V variant (High Affinity) - Jurkat Recombinant Cell Line Contact us for pricing
71273 2 vials ADCP Bioassay Effector Cell FcγRIIa (H variant) /NFAT Reporter-Jurkat Contact us for pricing
60405 2 vials AP-1 Reporter – HEK293 Recombinant Cell Line (JNK signaling pathway)
$1,250
60513 2 vials ARE reporter cell line (Nrf2 antioxidant pathway)
$1,250
60691 2 vials CD137 (4-1BB) HEK293 Recombinant Cell Line Contact us for pricing
60527 2 vials CD137L (4-1BBL) / TCR Activator- CHO-K1 Recombinant Cell Line Contact us for pricing
60523 2 vials CD137L (4-1BBL) CHO-K1 Recombinant Cell Line Contact us for pricing
60537 2 vials CD155 (PVR) - HEK293 Recombinant Cell Line Contact us for pricing
60548 2 vials CD155 / TCR Activator - CHO Recombinant Cell line Contact us for pricing
60624 2 vials CD27 CHO-K1 Stable Recombiant Cell Line Contact us for pricing
60626 2 vials CD40/NF-κB Reporter (Luc) - HEK293 Recombinant Stable Cell Line Contact us for pricing
71249 2 vials CD47 - HEK293 Cell Line Contact us for pricing
60602 2 vials CD47 CHO-K1 Cell line Contact us for pricing
60506 2 vials CFTR – HEK 293 Recombinant Cell Line Contact us for pricing
60515 2 vials CRE/CREB Reporter (Luc) – HEK293 Recombinant Cell Line (cAMP / PKA Signaling Pathway)
$1,250
60683-2 100 ml Dual Luciferase (Firefly-Renilla) Assay System
$1,050
60683-3 1 L Dual Luciferase (Firefly-Renilla) Assay System
$7,380
60683-1 10 ml Dual Luciferase (Firefly-Renilla) Assay System
$180
90334 2 vials Empty vector control - HEK293 Recombinant Cell line Contact us for pricing
60628 2 vials Foxp3 Reporter (Luc) - Jurkat Recombinant Cell Line Contact us for pricing
60656 2 vials GAL4 Reporter (Luc)-HEK293 Recombinant Cell Line
$775
60546 2 vials GITR / NF-κB Luciferase Reporter (Luc) - Jurkat Cell Line Contact us for pricing
79092 2 vials GITR - HEK293 Recombinant Cell Line Contact us for pricing
60547 2 vials GITRL CHO-K1 Recombinant Cell Line Contact us for pricing

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