TIGIT, Fc Fusion (Human) Recombinant

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Catalog #
71186
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Description

Recombinant human TGIT (T-cell immunoreceptor with Ig and ITIM domain), encompassing amino acids 22-141. This construct contains a C-terminal Fc region. The recombinant protein was affinity purified.

This product has been cited 2 times.

Synonyms
T-cell immunoreceptor with Ig and ITIM domains, V-set and immunoglobulin domain-containing protein 9, V-set and transmembrane domain-containing protein 3, VSIG9, VSTM3
Product Info
Storage and Usage
Citations2
Species
Human
Construct
TIGIT (22-141-Fc(IgG1))
Host Species/Expression System
HEK293
Purity

≥85%

Format
Aqueous buffer solution
Formulation

8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol

MW
40 kDa + glycans
Amino Acids
22-141
Glycosylation
This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Genbank #
NM_173799
UniProt #
Q495A1
Tag(s)
C-terminal Fc fusion (Human IgG1)
References
1. Yu, X., et al., Nat. Immunol. 2009; 10(1): 48-57.
2. Stanietsky, N., et al., Proc. Natl. Acad. Sci. (USA). 2009; 106(42): 17858-17863.