TIGIT, Fc fusion (Human)

Catalog #: 71186
Size: 100 µg
$310
Species: Human
Host Species: HEK293
MW: 39.7 kDa
Genbank #: NM_173799
Tag(s): C-terminal Fc fusion (Human IgG1)
a.a: 22-141
Description:
Human T-cell immunoreceptor with Ig and ITIM domains (TIGIT), also known as V-set and immunoglobulin domain-containing protein 9, VSIG9, V-set and transmembrane domain-containing protein 3, and VSTM3, GenBank Accession No. NM_173799, a.a. 22-141 fused to Fc region of human IgG, expressed in a HEK293 cell expression system. MW = 39.7 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.
UniProt
Q495A1
Synonym(s):
T-cell immunoreceptor with Ig and ITIM domains, V-set and immunoglobulin domain-containing protein 9, VSIG9, V-set and transmembrane domain-containing protein 3, VSTM3
Endotoxin Level:
<1 EU/μg
Formulation:
40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Format:
Aqueous buffer solution
Storage / Stability:
At least 6 months at –80°C.
Application(s):
Useful for studying protein binding and for screening small molecules and antibodies.
Reference(s):
1. Yu, X., et al., Nat. Immunol. 2009; 10(1): 48-57.
2. Stanietsky, N., et al., Proc. Natl. Acad. Sci. (USA). 2009; 106(42): 17858-17863.

Notes:
The aggregation state of this product has been confirmed to be <10%.
Warning(s):
Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 μg/ml in PBS + glycerol and stored at -80°C.
Scientific Category:
Immunotherapy
Product Type:
Fc fusion protein
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Product Datasheets

71186_Lot140701-D.pdf