Anti-CD19 Antibody, FITC-Labeled
This anti-CD19 antibody is a purified recombinant antibody, which is labeled with fluorescein isothiocyanate (FITC). This antibody has been tested by flow cytometry for specific binding to human CD19 on the surface of CD19 CHO Recombinant Cell Line (BPS Bioscience #79561).
≥90%
Aqueous buffer solution.
8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, 0.09% Sodium Azide, 0.2% BSA, and up to 20% glycerol. May contain a protein stabilizer.
Fluorescein isothiocyanate (FITC) is a derivative of fluorescein and has excitation and emission spectrum peak wavelengths of approximately 495 nm and 519 nm, causing it to fluoresce green.
CD19 (also known as Cluster of Differentiation 19, B-lymphocyte surface antigen B4, or CVID3) is a glycoprotein expressed at the surface of B lymphocytes through most phases of B cell maturation. It is strictly required for B cell terminal differentiation. Most B cell malignancies express normal to high levels of CD19, making it a nearly ideal target for cancer immunotherapy. CD19 was the target of the first approved CAR-T cell therapy. Studies of CD19 function and expression patterns will continue to broaden our knowledge and support possible applications in cancer therapy.
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