Anti-BCMA Antibody

Catalog #

101219

$295 *

Size: 100 µg

Qty

Bulk/Custom

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Description

This anti-BCMA antibody is a purified, recombinant human monoclonal antibody which recognizes the human BCMA protein. BCMA is also known as tumor necrosis factor receptor superfamily member 17 (TNFRSF17) and is expressed on the surface of plasma cells. BCMA is important for plasma cell differentiation and B cell proliferation. BCMA is a validated therapeutic target in multiple myeloma. The first anti-BCMA CAR-T cell therapy (idecabt agene vicleucel) was approved by the FDA in 2021.

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Synonyms

TNFRSF17, TNF receptor superfamily member 17, B-cell maturation protein, Tumor necrosis factor receptor superfamily member 17, BCM, BCMA, CD269, TNFRSF13A

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Product Data Gallery

4-20% SDS-Page Coomassie Staining

Binding assay of anti-BCMA and biotinylated human BCMA

Product Info

Storage and Usage

Citations

Species

Human

Isotype

IgG1

Clonality

Monoclonal

Host Species/Expression System

HEK293

Purity

≥90%

Purification

Protein A affinity chromatography from HEK293 supernatants

Format

Aqueous buffer solution

Formulation

8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, 20% glycerol

~146 kDa (Anti-BCMA HC: 50 kDa; Anti-BCMA LC: 23 kDa)

UniProt #

Q02223

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Datasheets/Protocols

101219 Lot 211020

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