3CL Protease, MBP-tag, His-tag (MERS-CoV) Recombinant

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Catalog #

100757

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Description

Middle East Respiratory Syndrome Coronavirus 3C-like protease (MERS-CoV 3CL Protease), GenBank Accession No. ATG84821.1, a.a. 1-306(full length), with an N-terminal MBP-tag, and C-terminal His-tag, expressed in an E. coli expression system, MW=78 kDa.

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Synonyms

3C-like protease, MERS protease, MERS-ncov protease, MERS-cov, MERS cov, merscov2, Mpro, Main protease, nsp5

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Product Data Gallery

4-20% SDS-PAGE Coomassie Staining

3CL Protease (MERS-CoV) Activity

3CL Protease (MERS-CoV) inhibition curve using a fluorogenic assay (#78278). Representative data only; data may vary by lot.

Product Info

Storage and Usage

Citations

Species

MERS-CoV

Host Species/Expression System

E. coli

Purity

>90%

Supplied As

Aqueous buffer solution.

Formulation

40 mM Tris-HCl, pH 8.0, 138 mM NaCl, 2.7 mM KCl, 20% glycerol, variable Imidazole.

78 kDa

Amino Acids

1-306(full length)

Genbank #

ATG84821.1

UniProt #

A0A291I686

Tag(s)

N-terminal MBP-tag, C-terminal His-tag

References

1. Jo, S. et al., J. Enzyme Inh. & Med. Chem. 2019; 1(35): 145-151.
2. He, J. et al., Intl J. Antimicrobial Agents. 2020; doi.org/10.1016/j.ijantimicag.2020.106055.

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3CL Protease, MBP-tag, His-tag (MERS-CoV) Recombinant

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