UBE2G1 (UBC7), His-Tag Recombinant
Catalog #
79372
$325
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Description
Recombinant full length human UBE2G1 (ubiquitin-conjugation enzyme E2 G1). This construct contains an N-terminal His-tag. The recombinant protein was affinity purified and is active.
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Synonyms
UBC7, E217K, UBE2G
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Product Data Gallery
Product Info
Storage and Usage
Citations
Species
Human
Construct
UBE2G1 (His-Full length)
Host Species/Expression System
E. coli
Purity
≥90%
Format
Aqueous buffer solution
Formulation
50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol.
MW
21 kDa
Specific Activity
11 pmol/min/µg
Genbank #
NM_003342
UniProt #
P62253
Background
UBE2G1 (UBC7) or ubiquitin-conjugating enzyme E2G 1 is a member of the E2 ubiquitin-conjugating enzyme family and catalyzes the covalent attachment of ubiquitin to other proteins which are involved in degradation of muscle-specific proteins. UBC7 is highly expressed in skeletal muscle (1). UBC7 is involved in the selective ubiquitylation of different substrates by the same E3 complex (2).
References
1. Watanabe, T.K., et.al., Cytogenet. Cell Genet. 1996; 74: 146-148.
2. Shibata, E., et al., Mol Cvell Biol. 2011 Aug.