Donepezil HCl

Catalog #: 27619-1
Size: 1 g
MW: 416 Da
CAS Registry #: 120011-70-3
Formula: C24H30ClNO3
Target: acetylcholinesterase (AChE)
Donepezil HCl is a piperidine-class AChE inhibitor containing an N-benzylpiperdine and an indanone moiety, which confers it a longer and more selective action against AchE as compared to BuChE (IC50: 7.4 µM). Donepezil HCl has been shown to improve cognitive function of mild to severe moderate AD patients and exhibits excellent tolerability without hepatotoxicity.
Aricept; 2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2,3-dihydroinden-1-one hydrochloride
Soluble in DMSO
Storage / Stability:

Store at or below –20°C. Solid form is stable at least 12 months from date of receipt, when stored as directed. Do not store aqueous solutions for more than one day.

Birks, J., Harvey, R.J . Cochrane Database Syst Rev. 2006 Jan 25;(1):CD001190.
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