HER2 Kinase Assay Kit

Catalog #: 40721
Size: 96 reactions
$695
Description:
HER2 (human epidermal growth factor receptor 2) encoded by ERBB2 gene has been found to be overexpressed in certain aggressive breast cancers, suggesting it as an important drug target as well as a biomarker. The HER2 Kinase Assay Kit is designed to measure HER2 kinase activity for screening and profiling applications using Kinase-Glo® MAX as a detection reagent.
Synonym(s):
HER2, NEU, ErbB2, TKR1, CD340, human epidermal growth factor receptor 2
Supplied As:
The HER2 Kinase Assay Kit comes in a convenient 96-well format, with enough purified recombinant HER2 enzyme, HER2 substrate, ATP and kinase assay buffer for 100 enzyme reactions.
Format:

Instructions for use:
See assay kit data sheet for detailed protocol.
Application(s):
Useful for studying enzyme kinetics and screening small molecular inhibitors for drug discovery and HTS applications.
Reference(s):
Tai, W. et al., Journal of Controlled Release 146(3):264-275 (2010)
Notes:

MATERIALS OR INSTRUMENTS REQUIRED BUT NOT SUPPLIED:
Kinase-Glo MAX (Promega, #V6071)
Dithiothreitol (DTT, 1 M; optional) 
Microplate reader capable of reading luminescence 
Adjustable micropipettor and sterile tips
30°C incubator

Scientific Category:
Kinase
Product Type:
Assay Kit
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Product Datasheets

40721.pdf