FGR, GST-tag Recombinant

Catalog #

40422

$410 *

Size: 10 µg

Qty

Bulk/Custom

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Description

Recombinant full-length human FGR was expressed by baculovirus in Sf9 insect cells using an N-terminal GST-tag. The gene accession number is NM_005248.

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Synonyms

SRC2, c-fgr, p55c-fgr

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Product Data Gallery

10% SDS-PAGE Coomassie Staining

Specific Activity

Product Info

Storage and Usage

Citations

Species

Human

Host Species/Expression System

Sf9 insect cells

Purity

≥90%

Format

Aqueous buffer solution

Formulation

50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.

86 kDa

Amino Acids

full length

Specific Activity

282 pmol/min/µg

Genbank #

NM_005248

UniProt #

P09769

Tag(s)

N-terminal GST-tag

Background

FGR is a protooncogene that is a unique member of the tyrosine kinase gene family. Certain lymphomas (but not sarcomas or carcinomas) express FGR-related messenger RNA. This transcript is detected in Burkitt's lymphoma cell lines naturally infected with Epstein-Barr virus (EBV), but not in EBV-negative Burkitt's lymphoma cells (1). FGR expression is limited to normal peripheral blood granulocytes, monocytes, and alveolar macrophages, all of which contain 50 to 100 copies of c-fgr mRNA per cell (2).

References

1. Cheah, MS. et al. Nature. 1986 Jan 16- 22,319(6050):238-40.
2. Willman, CL. et al. Proc Natl Acad Sci U S A. 1987 Jul,84(13):4480-4.

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FGR, GST-tag Recombinant

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