ROR1 CHO Recombinant Cell Line

Catalog #: 79609-H
Size: 2 Vials
$6,000
Catalog #: 79609-M
Size: 2 Vials
$6,000
Catalog #: 79609-L
Size: 2 Vials
$6,000
Background:
Tyrosine-protein kinase transmembrane receptor (ROR1) is an enzyme that in humans is encoded by the ROR1 gene. The ROR1 is expressed by tumor cells of various hematologic and solid malignancies and is largely absent from postnatal healthy cells and tissues. Treatment with a humanized monoclonal antibody specific for ROR1 (UC-961) can inhibit the capacity of ovarian cancer cells to migrate or engraft immune-deficient mice.
Description:
Recombinant clonal stable CHO cell line constitutively expressing full length human ROR1 protein (Genbank NM_005012.3). Surface expression of ROR1 was confirmed by flow cytometry. Each stable clonal cell line was selected for different levels of ROR1 expression (High, Medium, Low) to mimic different stages of cancer target cells with various ROR1 expression levels.
Synonym(s):
Neurotrophic tyrosine kinase, receptor-related 1, NTRKR1
Supplied As:
Each vial contains ~ 2.5 x 10^6 cells in 1 ml of Thaw Medium 3 + 10% DMSO.
Host Cell line:
CHO K1 cell line, Chinese Hamster Ovary
Mycoplasma Testing:
This cell line has been screened using the Quick Test Mycoplasma Detection Kit (Biotool.com, #B39032) to confirm the absence of Mycoplasma contamination.
Growth Media:

Thaw Medium 3 (BPS Bioscience, #60186):  Ham’s F-12 medium (Hyclone #SH30526.01) supplemented with 10% FBS (Life Technologies #26140-079), 1% Penicillin/Streptomycin (Hyclone #SV30010.01).

Growth Medium 3B (BPS Bioscience, #79529): Thaw Medium 3 (BPS Bioscience, #60186) plus 500 µg/ml Hygromycin (Thermo Fisher, #10687010).

Instructions for use:
See data sheet for detailed culturing and assay protocol.
Storage / Stability:
Store in liquid nitrogen immediately upon receipt.
Notes:
LICENSE DISCLOSURE:
Purchase of this cell line grants you with a 10-year license to use this cell line in your immediate laboratory, for research use only. This license does not permit you to share, distribute, sell, sublicense, or otherwise make the cell line available for use to other laboratories, departments, research institutions, hospitals, universities, or biotech companies. The license does not permit the use of this cell line in humans or for therapeutic or drug use. Inappropriate use or distribution of this cell line will result in revocation of the license and result in an immediate cease of sales and distribution of BPS products to your laboratory. Publications using this cell line should reference BPS Bioscience, Inc., San Diego.
Warning(s):

Avoid freeze/thaw cycles.

Scientific Category:
CAR T-Cell Therapy
Product Type:
Cell Lines
Data shown is lot-specific. Contact us for specific information on other lots.

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$5,500

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Product Datasheets

79609-H.pdf 79609-M.pdf 79609-L.pdf