PI3 kinase p110α (N345K)/p85α Recombinant

Catalog #

40646

$465 *

Size: 10 µg

Qty

Bulk/Custom

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Description

Complex of human p110α, also known as PIK3CA, GenBank Accession No. NM_006218, a.a. 2-1068(full length), with N345K mutation, with N-terminal His-tag, MW=111 kDa, and human p85α, also known as PIK3R1, GenBank Accession No. NM_181523, a.a. 1-724(full length), MW=85 kDa. Coexpressed in a Baculovirus infected Sf9 cell expression system.

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Synonyms

PIK3CA, PI3K, PI3 K, PI3-K, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform, Phosphoinositide 3-kinase alpha, PIK3R1, PI3-kinase regulatory subunit alpha

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Product Data Gallery

4-20% SDS-PAGE Coomassie Staining

Specific Activity

Product Info

Storage and Usage

Citations

Species

Human

Host Species/Expression System

Sf9 insect cells

Purity

≥80%

Formulation

50 mM sodium phosphate, pH 7.0, 300 mM NaCl, 150 mM imidazole, 0.1 mM PMSF, 0.25 mM DTT, 25% glycerol.

p110α (N345K): 111 kDa, p85α: 85 kDa

Amino Acids

p110α (N345K): 2-1068(full length), p85α: 1-724(full length)

Genbank #

p110α (N345K): NM_006218.2, p85α: NM_181523

UniProt #

p110α: P42336; p85α: P27986

Tag(s)

p110α: N-terminal His-Tag

References

1. Samuels, Y., et al. Science 304: 554 (2008)

2. Graupera, M., et al., Nature 453: 662-666 (2008)

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Datasheets/Protocols

40646 Lot 161216

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PI3 kinase p110α (N345K)/p85α Recombinant

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