LYNB, GST-tag Recombinant

Catalog #

40472

$410 *

Size: 10 µg

Qty

Bulk/Custom

Add to Favorites

*US Pricing only. For international pricing, please contact your local distributor.

●

Purchase

●

Description

Recombinant full-length human LYN B was expressed by baculovirus in Sf9 insect cells using an N-terminal GST-tag. The gene accession number is BC059394.

●

Synonyms

JTK8, FLJ26625, p65

●

Product Data Gallery

Product Info

Storage and Usage

Citations

Species

Human

Host Species/Expression System

Sf9 insect cells

Format

Aqueous buffer solution

Formulation

50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.

85 kDa

Amino Acids

full length

Specific Activity

235 pmol/min/µg

Genbank #

BC059394

UniProt #

P07948

Tag(s)

N-terminal GST-tag

Background

LYN is a 56 kd tyrosine kinase that is similar to mouse T-lymphocyte-specific tyrosine kinase p56lck, v-yes, v-fgr and v-src and is expressed in a variety of tissues (1). LYN is expressed preferentially in B cells and can be coimmunoprecipitated with IgM suggesting that LYN is physically associated with membrane-bound IgM, and participates in antigen-mediated signal transduction (2). Crosslinking of membrane-bound IgM with antibody induces rapid increase in activities of LYN and LYN-associated phosphatidylinositol 3-kinase.

References

1. Yamanashi, Y. et al. Mol Cell Biol. 1987 Jan;7(1):237-43.
2. Yamanashi, Y. et al. Science. 1991 Jan 11;251(4990):192-4.

Skip to the end of the images gallery

Skip to the beginning of the images gallery

LYNB, GST-tag Recombinant

PRODUCTS

SERVICES

RESOURCES

COMPANY