DLL1, Avi-Tag, His-Tag, Recombinant

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Catalog #

101805

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Description

Recombinant human DLL1 (delta like canonical Notch ligand 1), encompassing amino acids 18-540. This construct contains a C-terminal Avi-Tag™ followed by a His-tag (6xHis). The recombinant protein was affinity purified.

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Synonyms

Drosophila Delta homolog 1 (Delta1; H-Delta-1), Delta-like protein 1

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Product Data Gallery

4-20% SDS-PAGE Coomassie Staining

Product Info

Storage and Usage

Citations

Species

Human

Construct

DLL1 (18-540-Avi-His)

Host Species/Expression System

HEK293

Purity

≥90%

Format

Aqueous buffer solution.

Formulation

8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol

60 kDa + glycans

Amino Acids

18-540

Glycosylation

This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Genbank #

NM_005618.4

UniProt #

O00548

Tag(s)

C-terminal Avi-Tag™

Background

DLL1 is involved in cell-to-cell communication and in embryonic development, neurogenesis, and tissue homeostasis. It is a member of the Delta-Serrate-Lag2 (DSL) family of ligands that activate the Notch signaling pathway. DLL1 binds to the Notch receptors on neighboring cells, triggering signals that regulate cell fate determination, proliferation, and differentiation. Dysregulation of DLL1 has been implicated in several diseases.

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Datasheets/Protocols

101805 Lot 230522

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DLL1, Avi-Tag, His-Tag, Recombinant

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