B7-H2 (CD275, ICOSL), Fc fusion (Human) HiP™ Recombinant

Catalog #
71130
$320 *
Size: 100 µg
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Description

Human secreted B7 homolog 2 (B7-H2)-Fc fusion protein, also known as CD275, ICOSL, ICOSLG, and B7-related protein (B7RP), GenBank Accession No. NM_001283050, a.a 19-258 fused to human IgG1 Fc region (a.a. 100-330) and expressed in a HEK293 cell expression system. MW = 53.3 kDa (monomer). This protein runs at a higher MW by SDS-PAGE due to glycosylation.

Synonyms
B7 homolog 2, CD275, ICOSL, ICOSLG, B7-related protein (B7RP)
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
HEK293
Purity

≥90%

Format
Aqueous buffer solution
Formulation
40 mM Tris-HCl, pH 8.0. 110 mM NaCl, 2.2 mM KCl and 20% glycerol
MW
53.3 kDa
Amino Acids
19-258
Genbank #
NM_001283050
UniProt #
O75144
Tag(s)
C-terminal Fc fusion (Human IgG1)
References

1. Guillonneau, C., et al., Transplantation. 2005; 80(4): 546-554.
2. Fan, X., et al., J. Exp. Med. 2014; 211(4): 715-725.