Sestrin 2, FLAG-Tag Recombinant
Catalog #
50286
$425
*
●
●
Purchase
Description
Recombinant human sestrin 2 (SESN2), full length, encompassing amino acids 2-480(end). This construct contains an N-terminal Flag-tag. The recombinant protein was affinity purified.
●
Synonyms
Sestrin-2, HI95 SEST2, Hypoxia Induced Gene 95, SES2
●
Product Data Gallery
4-20% SDS-PAGE Coomassie Staining
Product Info
Storage and Usage
Citations
Species
Human
Construct
Sestrin 2 (FLAG-2-480(end))
Host Species/Expression System
Sf9
Purity
≥90%
Format
Aqueous buffer solution
Formulation
45 mM Tris-HCl, pH 8.0, 124 mM NaCl, 2.4 mM KCl, 3 mM DTT, 100 µg/ml FLAG peptide, and 10% glycerol
MW
55 kDa
Amino Acids
2–480(end)
Genbank #
NM_031459
UniProt #
P58004
Background
Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. Sestrin 2 is involved in cellular response to different stress conditions and is involved in the reduction of peroxiredoxins.
References
1. Lee, J.H., et al. (2010). Science 327(5970): 1223-8.
2. Broderick, G., et al., (2006). Pharmacogenomics 7(3): 407-419.
3. Budanov AV, Karin M. (2008). Cell 134 (3): 451-460.
4. Hay, N. (2008). Cell Metab. 8(3):184-5.
2. Broderick, G., et al., (2006). Pharmacogenomics 7(3): 407-419.
3. Budanov AV, Karin M. (2008). Cell 134 (3): 451-460.
4. Hay, N. (2008). Cell Metab. 8(3):184-5.
Powered by Bioz
6405 Mira Mesa Blvd. Suite 100
San Diego, CA 92121
858-202-1401
San Diego, CA 92121
858-202-1401
Products are for Research Use Only
COMPANY
Copyright © 2024
BPS Bioscience, Inc.
All rights reserved.
Diagrams on this website are created with BioRender.com.