400 µM S-Adenosylmethionine

Catalog #: 52120
Size: 250 µL
$200
MW: 398.4 Da
CAS Registry #: 29908-03-0
Formula: C15H22N6O5S
Background:
S-Adenosylmethionine (AdoMet or SAM) plays a pivotal role as a methyl donor in a myriad of biological and biochemical events. It is a cofactor for enzyme-catalyzed methylations, including catechol O-methyltransferase (COMT) and DNA methyltransferases (DNMT). Although present in all cells, it is concentrated in liver where 85% of all methylation reactions occur. It is also involved in regulating liver function, growth, and response to injury.
Description:
S-(5’-Adenosyl)-L-methionine solution. Useful as a methionine donor in methyltransferase assays.
Synonym(s):
S-Adenosylmethionine, AdoMet, SAM, S-Adenosyl-L-methionine, SAMe
Supplied As:
400 µM solution in water
Format:
Aqueous buffer solution
Storage / Stability:

At least 6 months from date of receipt, when stored as directed

Reference(s):
1. Chiang, P.K., et al. FASEB J. 1996 Mar;10(4):471-80.
2. Lu SC, Mato JM. Physiol Rev. 2012 Oct;92(4):1515-42.
3. Finkelstein JD. Clin Chem Lab Med. 2007;45(12):1694-9.
Warning(s):
Avoid freeze/thaw cycles.
Scientific Category:
Methyltransferase
Product Type:
Reagent
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Product Datasheets

52120_Lot110603.pdf