Rat Renin, His-tag Recombinant

Catalog #

80201

$435 *

Size: 100 µg

Qty

Bulk/Custom

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Description

Rat, Activated Renin (GenBank Accession No. NM_012642), a.a. 65 – 402 (end) with C-terminal His-tag, MW=38.5 kDa, expressed in an HEK293 cell expression system.

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Synonyms

Angiotensinogenase

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Product Data Gallery

10% SDS-PAGE Coomassie Staining

Specific Activity

Product Info

Storage and Usage

Citations

Species

Rat

Host Species/Expression System

HEK293 cells

Purity

≥90%

Format

Aqueous buffer solution

Formulation

40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.

38.5 kDa

Amino Acids

65–402 (end)

Genbank #

NM_012642

UniProt #

P08424

Tag(s)

C-terminal His-tag

Background

Renin is a protease that is synthesized by the kidneys. Renin catalyzes the hydrolysis of angiotensinogen to angiotensin I, which is converted to angiotensin II, a highly potent vasoconstrictor. Renin inhibitors have been used therapeutically in the treatment of hypertension (high blood pressure).

References

1. Kedrah, AE., et al., Kidney Blood Press Res. 2012 Jun 6;35(6):425-430.
2. Burnham, CE., et al., Proc Natl Acad Sci USA. 1987 Aug;84(16):5605-5609.

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Datasheets/Protocols

80201_Lot120809-GC.pdf

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Rat Renin, His-tag Recombinant

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