PKD2, GST-tag Recombinant

Catalog #

40168

$410 *

Size: 10 µg

Qty

Bulk/Custom

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Description

Recombinant human PKD2, full length, with N-terminal GST-tag, expressed in Sf9 insect cells via a baculovirus expression system.

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Synonyms

HSPC187; DKFZp586E0820; PRKD2

Product Info

Storage and Usage

Citations

Species

Human

Host Species/Expression System

Sf9 insect cells

Purity

≥75%

Format

Aqueous buffer solution

Formulation

50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, 0.1 mM EDTA, 0.1 mM PMSF, 25% glycerol.

130 kDa

Amino Acids

full length

Genbank #

NM_016457

UniProt #

Q9BZL6

Tag(s)

N-terminal GST-tag

Background

PKD2 is a novel phorbol ester- and growth factor-stimulated serine/threonine kinase that contains two cysteine-rich motifs at the N terminus, a pleckstrin homology domain, and a catalytic domain (1). It exhibits the strongest homology to the serine/threonine protein kinases PKD/PKCµ and PKCν. The PKD family of enzymes have been implicated in very diverse cellular functions, including Golgi organization and plasma membrane directed transport, metastasis, immune responses, apoptosis and cell proliferation (2).

References

1. Sturany, S. et al: Molecular cloning and characterization of the human protein kinase D2. A novel member of the protein kinase D family of serine threonine kinases. J Biol Chem. 2001 Feb 2;276(5):3310-8.
2. Rykx, A. et al: Protein kinase D: a family affair. FEBS Lett. 2003 Jul 3;546(1):81-6.

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PKD2, GST-tag Recombinant

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