Oxamflatin

Catalog #

27201

$150 *

Size: 1 mg

Qty

Bulk/Custom

Add to Favorites

*US Pricing only. For international pricing, please contact your local distributor.

●

Purchase

●

Description

Oxamflatin is a potent inhibitor of histone deacetylases. It has the ability to alter expression of genes involved in cell morphology, motility, apoptosis and cell cycle control, reducing the proliferation of cancer cells.

●

Product Data Gallery

Product Info

Storage and Usage

Citations

Purity

≥95% by HPLC.

Format

White to off-white crystalline solid

Formula

C₁₇H₁₄N₂O₄S

342.4 Da

Solubility

Solubility in ethanol, DMSO and DMF is 0.5 mg/ml, 5 mg/ml, and 10 mg/ml respectively. Sparingly soluble in aqueous buffers.

Biological Activity

Oxamflatin inhibits histone deacetylases with IC50 = 15.7 nM.

CAS Registry #

151720-43-3

References

1. Kim, Y.B., et al., Oncogene 1999; 18: 2461-2470.
2. Peart, M.J., et al., Cancer Res 2003; 63: 4460-4471.
3. Dear, A.E., et al., Biochem. Biophys. Acta 2000; 1492: 15-22.

Skip to the end of the images gallery

Skip to the beginning of the images gallery

Oxamflatin

PRODUCTS

SERVICES

RESOURCES

COMPANY