Ellagic acid

Catalog #

27219

$105 *

Size: 100 mg

Qty

Bulk/Custom

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Description

Ellagic acid, also known as TBBD, Gallogen, and Lagistase, can alter cytochrome P450 activity, and improve metabolism and clearance of xenobiotics, as well as alter immune function. It can also block methylation of arginine 17 of histone 3 (H3R17) by coactivator-associated arginine methyltransferase 1 (CARM1), or PRMT4, without significantly altering histone acetylase or DNA methyltransferase activity.

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Synonyms

Ellagic acid, TBBD, Gallogen, Lagistase

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Product Data Gallery

Product Info

Storage and Usage

Citations

Purity

≥95% by HPLC

Format

A crystalline solid.

Formula

C₁₄H₆O₈

302.2 Da

Solubility

Soluble in DMSO, purged with an inert gas. Solubility in DMSO is ~0.14 mg/ml.

Biological Activity

Ellagic acid was found to partially inhibit CARM1, even at an inhibitor concentration 10-fold above the IC50 of 25 µM.

CAS Registry #

476-66-4

References

1. Allen, C.T., et al. Immunopharmacol. Immunotoxicol. 2003; 25(3):409-422.
2. Herber, D., et al., Cancer Lett. 2008; 269:262-268.
3. Girish, C., et al., Fundam. Clin. Pharmacol. 2008; 22:623-632.

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Ellagic acid

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