S-adenosyl homocysteine, Fluorescein-labeled
Catalog #
52012
$320
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Description
S-adenosyl homocysteine conjugated to fluorescein.
This product has been cited 1 time.
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Synonyms
FITC-SAH, AdoHCys-FITC, S-adenosyl homocysteine, FITC, SAH-FITC
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Product Data Gallery
Product Info
Storage and Usage
Citations1
Supplied As
DMSO solution (12.5 µM)
Format
DMSO solution
MW
773.8 Da
CAS Registry #
979-92-0 (SAH)
Background
S-Adenosyl-L-homocysteine is an amino acid derivative used in several metabolic pathways in most organisms. S-Adenosyl-L-homocysteine (SAH) is an amino acid derivative and an intermediate, by-product, or modulator of several metabolic pathways, including the activated methyl cycle and cysteine biosynthesis. SAH is formed by the demethylation of S-adenosyl-L-methionine. It is also a product of S-adenosyl-methionine (SAM)-dependent methylation of biological molecules, including DNA, RNA, and histones and other proteins. Inhibitors that block its hydrolysis are being developed as anti-viral, anti-parasitic, anti-arthritic and immunosuppressive agents.
References
1. Coward JK, Slisz EP. J Med Chem. 1973 May;16(5):460-3.
2. Finkelstein JD. Clin Chem Lab Med. 2007;45(12):1694-9.
Application Reference(s):
1. Cooperative and Mechanistic Roles of Mecom in Hematopoiesis (2019)
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