Human α Thrombin
Catalog #
80111
$200
*
●
●
Purchase
Description
The Human Thrombin was activated from homogeneous human prothrombin by activation with Factor Xa, Factor Va, and phospholipid. These activating enzymes were removed after activation. Complete activation was observed on SDS-PAGE. The above protein was purified from Human plasma units that test negative for antibodies to HBc, HCV, HIV 1/2, HTLV-I/II, and non-reactive for HBsAg, HIV-1 RNA, HCV RNA, HBV DNA and Syphilis by FDA approved tests. Donors are screened for CJD.
●
Synonyms
alpha thrombin, Coagulation factor II
Product Info
Storage and Usage
Citations
Species
Human
Purity
≥90% by SDS-PAGE
Purification
Purified from human plasma that was tested and found negative by FDA-accepted methods for Anti-HIV1/2, Anti-HTLV I & II, HBsAg, Anti-HCV, Syphilis, HBC Ab, HIV-1 p24 Ag or HIV-1 RNA, HCV RNA and HBV RNA. Donors are screened for CJD (Creutzfeldt-Jakob Disease).
Format
Aqueous buffer solution
Formulation
50 mM sodium citrate, 0.2 M NaCl, 0.1% PEG-8000, pH 6.5
MW
37 kDa
Specific Activity
3027 NIH units/mg
UniProt #
P00734
Background
Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing.
References
1. Spronk HM, et al. 2013. Curr Atheroscler Rep. 15(11):363.
2. Huntington JA. 2013. J Thromb Haemost. Suppl 1:254-64.
2. Huntington JA. 2013. J Thromb Haemost. Suppl 1:254-64.
Powered by Bioz
6405 Mira Mesa Blvd. Suite 100
San Diego, CA 92121
858-202-1401
San Diego, CA 92121
858-202-1401
Products are for Research Use Only
COMPANY
Copyright © 2024
BPS Bioscience, Inc.
All rights reserved.
Diagrams on this website are created with BioRender.com.