Fluorogenic DPP substrate1

Catalog #: 80305
Size: 100 µl
MW: 477.5 Da
Formula: C26H27O6N3
The fluorogenic DPP substrate 1 is a Ala-Pro-AMC dipeptide. It can be used for the activity assays of DPP4, DPP7, DPP8, DPP9, FAP, and prolyl oligopeptidase (POP). λex 353-380 nm, λem=440-460 nm
Ala-Pro-AMC, A-P-AMC
Supplied As:
0.5 mM solution in DMSO (100 µl)
DMSO solution
Storage / Stability:

Stable at least 6 months from date of receipt, when stored as directed

Useful for the study of DPP activity, and for screening small molecule inhibitors of DPP4, DPP7, DPP8, DPP9, FAP, and POP for drug discovery and HTS applications. Also suitable for use with Xaa-Pro dipeptidase.

1. Park, J.E., et al., J. Biol. Chem., 274, 36505 (1999).
2. Sun, S., et al., Protein Expr. Purif., 24, 274 (2002).

Application Reference(s):
1. Design, synthesis and anti-diabetic activity of triazolotriazine derivatives as dipeptidyl peptidase-4 (DPP-4) inhibitors (2017)

Protect from direct exposure to light. Avoid freeze/thaw cycles.
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