Human Fibroblast Growth Factor 21 Recombinant
Catalog #
90134-A
$130
*
●
●
Purchase
Description
Recombinant Fibroblast Growth Factor 21 is a disulfide-linked monomer protein consisting of 182 amino acid residues, and migrates as an approximately 20 kDa protein under non-reducing and reducing conditions in SDS-PAGE. Optimized DNA sequence encoding Human Fibroblast Growth Factor-21 mature chain was expressed in E. coli.
●
Synonyms
FGF-21, Fibroblast Growth Factor-21
Product Info
Storage and Usage
Citations
Species
Human
Host Species/Expression System
E. coli
Purity
≥96% by SDS-PAGE and HPLC
Format
lyophilized protein
Formulation
Lyophilized from 0.2 µm filtered PBS solution, pH 7.0.
MW
20 kDa
Endotoxin Level
<0.1 ng/µg (1 EU/µg), using the LAL gel clot method.
Amino Acids
29–209
Genbank #
Q9NSA1
UniProt #
Q9NSA1
Background
FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic
development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-21 stimulates glucose uptake in differentiated adipocytes via the induction of glucose transporter SLC2A1/GLUT1
expression (but not SLC2A4/GLUT4 expression). Activity requires the presence of KLB.
References
1. Teillon, S., et al. J Endocrinol. 2010 Apr,205(1):37-47.
2. Suzuki, M., et al. Mol. Endocrinol., Apr 2008, 22: 1006 - 1014.
2. Suzuki, M., et al. Mol. Endocrinol., Apr 2008, 22: 1006 - 1014.
Powered by Bioz
6405 Mira Mesa Blvd. Suite 100
San Diego, CA 92121
858-202-1401
San Diego, CA 92121
858-202-1401
Products are for Research Use Only
COMPANY
Copyright © 2024
BPS Bioscience, Inc.
All rights reserved.
Diagrams on this website are created with BioRender.com.